The purpose of this study is to investigate the effectiveness of case study on student learning using Laboratory for Innovative Technology and Engineering Education (LITEE) case study. It has been proposed that student learning outcomes will be improved after using the case analysis. Seven constructs have been developed to measure different aspects related to student learning. Pre-assessment and post-assessment of student learning outcomes has been conducted to determine the effectiveness of case study approach in enhancing student learning. The results show that using case analysis significantly improves students’ higher-order cognitive domain of learning (HC) and self-efficacy (SE). The paper makes contribution to our understanding of the effectiveness of case study on improving learning outcomes of undergraduate students in operations management. Implications for educators and future research have been outlined.